Creatine Monohydrate vs. Creatine HCL: Which One Should You Choose?
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Creatine is one of the most researched and effective supplements for improving strength, muscle growth, and exercise performance and recovery. It’s widely available in two forms: Creatine Monohydrate vs. Creatine HCL. But which one is better? Let’s dive in.

What Exactly is Creatine?
Creatine is a naturally occurring compound found in muscle cells that helps your muscles produce energy. It can be found naturally in foods such as red meat, poultry, and fish. It’s often taken in supplement form by athletes and bodybuilders. Supplementing with creatine essentially supercharges your muscles’ energy reserves. Studies show that supplementing with creatine improves performance, strength, and muscle recovery.
How much should I take?
The current literature suggests starting creatine supplementation at 0.3 grams/kg/day of creatine monohydrate for at least 3 days (often called the loading phase) and then upping the dosage to 3–5 g/day for maintenance. This dosage method allows the body to build up a store of creatine. Some athletes may skip the loading phase and stick to 3–5 grams per day, which can also be effective but there isn’t as much evidence supporting this method.
Creatine Monohydrate vs. Creatine HCL
Creatine monohydrate is a widely studied supplement known for increasing muscle strength, enhancing performance, and supporting recovery by boosting ATP production, promoting muscle growth, and improving overall exercise capacity.
Pros:
- Most Researched – Backed by decades of studies proving its effectiveness.
- Highly Effective – Increases strength, power, and muscle mass.
- Affordable – The most cost-effective form of creatine.
Cons:
- Water Retention – This may cause slight bloating due to increased water retention in muscles.
- Possible GI Issues – Some people report mild stomach discomfort.
Creatine Monohydrate vs. Creatine HCL
Creatine HCL supports muscle growth and strength gains similar to creatine monohydrate while enhancing anabolic hormone levels, boosting recovery, and reducing stress-related hormones that contribute to muscle breakdown.
Pros:
- More Soluble – Dissolves better in water, which may improve absorption.
- Lower Dosage Needed – Due to better absorption, lower doses (1-2g) may be effective.
- Less Water Retention – May reduce bloating compared to monohydrate.
- Fewer Digestive Issues – Some people tolerate HCL better due to its solubility.
Cons:
- More Expensive – Costs significantly more than creatine monohydrate.
- Less Research – Fewer studies have proven its effectiveness
- No Proven Performance Advantage – There is currently no strong evidence that it’s more effective than monohydrate.
Which One Should You Choose?
- For Most People: Creatine Monohydrate – It’s cheaper, well-researched, and highly effective.
- If You Have Digestive Issues with Monohydrate: Creatine HCL may be worth trying.
- If You Want to Avoid Water Retention: HCL might be preferable, but it’s important to note, that water retention is not fat gain—is beneficial for muscle hydration.

Bottom Line
Creatine monohydrate remains the gold standard due to its affordability, availability, extensive research, and effectiveness. While creatine HCL is promising, its benefits over monohydrate are still theoretical and come with a higher price tag. Regardless, creatine in both forms will improve your creatine stores, boosting your performance, strength, and recovery. My suggestion, try monohydrate first. If you experience bloating, water retention, or other digestive discomfort, try switching to creatine HCL.
However, eating more protein does not necessarily increase creatinine levels unless it leads to higher muscle mass or increased creatine supplementation. Elevated creatinine levels in blood tests are often used as a marker of kidney function rather than protein intake.
You may also be interested in Exploring Milk Protein Concentrate (MPC) vs. Milk Protein Isolate (MPI) and Top 10 Protein Bars for Diabetics.